One cannot change who they are
You cannot change yourself.
The inherent traits in a person remain as they are even if they actively seek to change them
He is bound to lose the game again, a Leopard cannot change his spots after all.
She is still going after me. It's impossible for a Leopard to change his spots.
He was a great guy at school and he’s a great now , a leopard can’t change its spots.
There is no origin for this idiom
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definition
Common phrase that has a specific meaning.