to want to revenge or punish someone, because they have made you angry
to get very angry with someone and finding them to harm or punish
to be very angry with someone and threatening to harm them
John is after blood who damage his car in the parking.
Merry said that she is looking for you everywhere. She’s after your blood.
I suggest you stay away from him as he is after your blood now.
I don’t know why he is after my blood. I have done nothing wrong with him.
He has duped many people and now they are after his blood.
There is no origin for this idiom
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definition
Common phrase that has a specific meaning.