with absolute certainty
as would be expected and is of no surprise
can also be used as an informal affirmation that what you are saying is true
used as a polite way of giving someone permission
can also be used to mean “as luck would have it”
Of course, I will help you to move. That’s what friends are for.
I can’t believe that you doubted me. Of course, I remembered to bring your bag with me.
He will, of course, be the first person out the door today. It is after all a long weekend.
“Do you like my new hairstyle?” “Of course.”
“Could I please run in and use your printer? Mine has just broken.” “Of course, help yourself.”
Of course, my car would be giving trouble today. As if I don’t have enough to worry about.
There is no origin for this idiom
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definition
Common phrase that has a specific meaning.